Playing the Indian Card

Friday, April 17, 2020

The Darkest Hour Is Just Before Dawn





Scott Adams, the genius behind Dilbert, has pretty much given up hope on hydroxychloraquine. We’re all going to get the virus, he figures, and all we can do is take our chances.

Adams is a very smart guy, who also hears behind the scenes, he says, from a lot of other people. He says there has been more than enough time for the results of the first proper controlled studies in the US to have become apparent. Studies still have to be written up, but if the hydroxychloraquine combination worked decisively, it would by now be apparent. So if we have not heard anything, it must be that it does not work. 

Too bad, because up until a few days ago, Adams was quite hopeful about hydroxychloraquine, and was hinting at some very good news soon. Things he knew that the general public did not know yet.

I disagree with his current conclusion. I think Scott Adams is smart enough that he does not believe it either. I think if the studies so far had shown hydroxychloroquine did not work, we would also have likely heard by now. In fact, we would have been more likely to hear if it had not worked than if it had. We hear such things through the media, and the media have been out to discount it, to get at Trump, because he’s been speaking of it as promising. Any leak suggesting it did not work would therefore be prominently reported. Those involved in the studies would probably be approached by media, if they are doing their job, and coaxed to spill it if it did not work.

A leak suggesting it really did work would be much more likely to be buried. That would help Trump.

Even if it did work, and work well, there would be an incentive to bury this fact even for Trump and the administration.

Trump boasts that the US has 29 million doses of the hydroxychloroquine. No word on how much azithromycin. Twenty-nine million doses sounds like a lot. But according to the French study, five doses are needed to cure a typical case of coronavirus.

That’s enough to treat six million people, then. That still sounds like a lot.

But the word is that the treatment is only effective if given early, at the onset of symptoms. It cannot be held back for only the worst cases; to work, it must be given promptly to anyone with symptoms.

Now imagine it becomes publicly known that the hydroxychloroquine treatment is almost always effective, if given early.

There would be an immediate demand to end the lockdowns and get back to work. People are desperate. Even if the lockdowns were not immediately lifted, people would ignore them. Everyone would pour out onto the streets and form conga lines.

Experts estimate that, without the lockdown, 60% of the population will soon become infected. Roughly 200 million people in the US alone.

That means, in such a scenario, the US alone would need 200 million times five doses: a billion doses. Not 29 million.

And wait; there’s more. There are some reports that the drug is prophylactic. Take it regularly, and, as with malaria, you don’t get the illness, or the symptoms, in the first place. If that gets out, the demand will not be for five doses for 60% of the population, but five doses a month for 100% of the population, indefinitely.

In the meantime, you need to assure a secure supply for first-line medical workers, and for those already taking the drug for lupus and other ailments.

So if it works very well, there is a huge incentive to keep this quiet.

Notice that just about the same situation was behind the early assurances that masks were ineffective. Yes, they were always effective, but there were not enough of them, and they were needed for medical personnel.

But if hydroxychloroquine is effective, and this is now well-established, it explains why Trump feels it is now possible to start cautiously opening things up. Cautiously, and without revealing how effective the treatment is, so that numbers infected do not outstrip supplies.

I suspect that Adams, if he indeed has lots of contacts, has been gotten to and had this explained to him. He has been asked to dampen expectations so that it all works.

Trudeau had just announced that Canada would need to remain in lockdown until late summer, and Duterte in the Philippines just said the same. This, presumably, is the difference between knowing about and having hydroxychloroquine, and not having it. Without it, this is what the medical models suggest is necessary.

I expect that, behind the scenes, the US is doing what is necessary to increase their supply. Whether that includes invading Venezuela or not.

At the same time, there are early promising reports about another drug, remdesivir. The stock market was up yesterday on the news. This one was leaked. Remdesivir is a lot more expensive than hydroxychloroquine, but it seems to be effective with the most extreme cases, exactly those with which hydroxychloroquine is reportedly ineffective. For this reason, it can be safely announced even if available only in small quantities.

The two together might cover the zone.


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